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24 Oct 2017

What is an open label extension study?

  • An openlabel trial or open trial is a type of clinical trial in which both the researchers and participants know which treatment is being administered.
  • This contrasts with single blind and double blind experimental designs, where participants are not aware of what treatment they are receiving (researchers are also unaware in a double blind trial).
  • Open-label trials may be appropriate for comparing two very similar treatments to determine which is most effective.
  • An open-label trial may be unavoidable under some circumstances, such as comparing the effectiveness of a medication to intensive physical therapy sessions.

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