24 Oct 2017
- An open–label trial or open trial is a type of clinical trial in which both the researchers and participants know which treatment is being administered.
- This contrasts with single blind and double blind experimental designs, where participants are not aware of what treatment they are receiving (researchers are also unaware in a double blind trial).
- Open-label trials may be appropriate for comparing two very similar treatments to determine which is most effective.
- An open-label trial may be unavoidable under some circumstances, such as comparing the effectiveness of a medication to intensive physical therapy sessions.